Current Positions
Dean, College of Pharmaceutical Sciences, NYCU
Distinguished Professor in Institute of Biopharmaceutical Sciences
Director in Chong Hin Loon Memorial Cancer and Biotherapy Research Center
Director in Ph.D. Program in Regulatory Science and Policy
Board Director at Intech Biopharm Corporation. (Legal Representative of the National Development Fund, Executive Yuan (NDF, EY))
Board Director at Genovate Biotechnology Co, Ltd. (Legal Representative of NDF, EY)
Joint appointments: Institute of Clinical Medicine, Institute of Biomedical Informatics and Department of Biotechnology and Laboratory Science in Medicine
Joint appointments: Department of Biochemistry, Kaohsiung Medical University
Contact
TEL:02-28267000 #67381
Email:cyhuang5@nycu.edu.tw
Office:RM.217, 2F., Nursing Building
Education
Ph.D. in Biochemistry and Biophysics (Laboratory of Donald J. Graves, Iowa State University)
Research Interest
Drug repurposing for the treatment of cancer and disease, development of drug-biomarker pairs for precision medicine
Drug development:
CY001: Development of cancer stem cell chemical inhibitor for lung adenocarcinoma. Currently, CY001 has complete the phase 1b clinical trial.
YQ1: Development of cancer stem cell inhibitor (herbal medicine YQ1) for lung adenocarcinoma. Currently, YQ1 has complete the phase 2 clinical trial.
Exosome or Extracellular vesicles (EV):
There are many possible clinical applications, and we have also applied the properties of EVs for early screening and prognostic monitoring of cancer.
Major awards and honors:
The 14th National Innovation Award (2017)
The 18th National Innovation Award (2021)
2024 Future Tech Award (2024)
Prior Positions
2020-2023 Chairman in Institute of Biopharmaceutical Sciences, NYCU
2019-2022 Board Director at PharmaEngine Inc. (Legal Representative of NDF, EY)
2018-2020 Deputy Director in Biomedical Engineering Research and Development Center, NYCU
2018-2020 Coach of SPARK program at National Yang Ming Chiao Tung University
2011-2019 Professor in Institute of Biopharmaceutical Sciences, National Yang-Ming University
2011-2017 Chairman in Institute of Biopharmaceutical Sciences, National Yang-Ming University
2007-2011 Professor in Institute of Clinical Medicine, National Yang-Ming University
2005-2007 Associate Investigator in Institute of Cancer Research, National Health Research Institutes
2003-2005 Associate Investigator in Division of Molecular and Genomic Medicine, NHRI
1998-2003 Assistant Investigator in Division of Molecular and Genomic Medicine, NHRI
1994-1998 Postdoc in Molecular Pharmacology (Laboratory of James E. Ferrell, Jr., Stanford University)
Research
Selected corresponding author publications: (214 papers)
- Extracellular Vesicular Delta-Like Ligand 3 and Subtype Transcription Factors for Small Cell Lung Cancer Diagnosis. Advanced Science 12(22):e2416711 (2025)
- Repurposing pitavastatin and atorvastatin to overcome chemoresistance of metastatic colorectal cancer under high glucose conditions. Cancer Cell International 25(1):79 (2025)
- Utilizing TP53 hotspot mutations as effective predictors of gemcitabine treatment outcome in non-small-cell lung cancer. Cell Death Discovery 11:26 (2025)
- Engineered Extracellular Vesicles Carrying Let-7a-5p for Alleviating Inflammation in Acute Lung Injury. Journal of Biomedical Science 31:30 (2024)
- Extracellular Vesicular Analysis of Glypican 1 mRNA and Protein for Pancreatic Cancer Diagnosis and Prognosis. Advanced Science 11:e2306373 (2024)
- Dual targeted extracellular vesicles regulate oncogenic genes in advanced pancreatic cancer. Nature Communications 14:6692 (2023)
- Repurposing thioridazine for inducing immunogenic cell death in colorectal cancer via eIF2α/ATF4/CHOP and secretory autophagy pathways. Cell Communication and Signaling 21:184. (2023)
- BMX, a specific HDAC8 inhibitor, with TMZ for advanced CRC therapy: a novel synergic effect to elicit p53-, β-catenin- and MGMT-dependent apoptotic cell death. Cell Communication and Signaling 20(1):200. (2022)
- Mesenchymal stem cell secreted-extracellular vesicles are involved in chondrocyte production and reduce adipogenesis during stem cell differentiation Tissue Engineering and Regenerative Medicine 19:1295–1310 (2022)
- Identification of Thioridazine, an antipsychotic drug, as an antiglioblastoma and anticancer stem cell agent using public gene expression data. Cell Death and Disease 6:e1753 (2015).
- Trifluoperazine, an antipsychotic agent, inhibits cancer stem cell growth and overcomes drug resistance of lung cancer. American Journal of Respiratory and Critical Care Medicine, 186(11):1180-1188 (2012)
First and Second Dean (2016 to July 2022)

Professor Kang, Jaw-Jou
Position
Institute of Food Safety and Health Risk Assessment, NYCU Emeritus Professor
Degree
Ph.D. in Chemistry, UCSD
Specialty
◆Cellular and molecular Toxicology
◆ Effects of chemicals and drugs on receptors and enzymes of plasma membranes
◆ Roles of calcium in chemically induced cytotoxicity
Third Dean (August 2022 to July 2025)

Professor Anya Maan-Yuh Lin
Position
Acting Director in Institute of Food Safety and Health Risk Assessment
Professor of Pharmacy Department
Joint appointments: Ph.D. Program in Regulatory Science and Policy, Institute of Biopharmaceutical Sciences, Institute of Pharmacology, Department & Institute of Physiology
Degree
PhD, Pharmacology, Colorado State University, USA
Specialty
CNS Neuropharmacology, Translational research
